Exploring mechanisms of lung injury and repair
To discover new treatments for individuals with critical illness
tRNAs as uncharacterized, functioning biomarkers in acute respiratory distress syndrome (ARDS)
tRNAs are increasingly acknowledged as essential regulators in various human diseases; however, their role in critical illness has yet to be explored.
Molecular profiling of individuals with critical illnesses
We utilize our extensive ICU biorepository, which includes longitudinal samples from critically ill patients, to elucidate disease mechanisms and discover new targets for further research.
Protein degradation in ARDS and sepsis
Ubiquitination is a universal molecular modification that tags proteins for degradation and governs vital cellular processes, such as cell death and responses to environmental stimuli.
