Discover the latest research conducted by Dr. Bednash and team.
This page is frequently updated, so stay tuned for new topics and publications!
2024
Synergy Between NK Cells and Monocytes in Potentiating Cardiovascular Disease Risk in Severe COVID-19
Gunasena M, Alles M, Wijewantha Y, Mulhern W, Bowman E, Gabriel J, Kettelhut A, Kumar A, Weragalaarachchi K, Kasturiratna D, Horowitz JC, Scrape S, Pannu SR, Liu SL, Vilgelm A, Wijeratne S, Bednash JS, Demberg T, Funderburg NT, Liyanage NPM
Arteriosclerosis, Thrombosis, and Vascular Biology • October 2024 • PMID: 38989579
Neutralization escape, infectivity, and membrane fusion of JN.1-derived SARS-CoV-2 SLip, FLiRT, and KP.2 variants
Li P, Faraone JN, Hsu CC, Chamblee M, Zheng Y-M, Carlin C, Bednash JS, Horowitz JC, Mallampalli RK, Saif LJ, Oltz EM, Jones D, Li J, Gumina RJ, Xu K, Liu S-L
Cell Reports • 27 August 2024 • PMID: 39024099
Longitudinal transcriptomic analysis reveals persistent enrichment of iron homeostasis and erythrocyte function pathways in severe COVID-19 ARDS
Eltobgy M, Johns F, Farkas D, Leuenberger L, Cohen SP, Ho K, Karow S, Swoope G, Pannu S, Horowitz JC, Mallampalli RK, Englert JA, Bednash JS
Frontiers in Immunology • 5 August 2024 • PMID: 39161760
Targeted degradation of extracellular mitochondrial aspartyl-tRNA synthetase modulates immune responses
Johnson BS, Farkas D, El-Mergawy R, Adair JA, Elhance A, Eltobgy M, Coan FM, Chafin L, Joseph JA, Cornwell A, Johns FJ, Rosas L, Rojas M, Farkas L, Bednash JS, Londino JD, Ray P, Ray A, Kagan V, Lee JS, Chen BB, Mallampalli RK
Nature Communications • 22 July 2024 • PMID: 39039092
SCARLET (Supplemental Citicoline Administration to Reduce Lung injury Efficacy Trial): study protocol for a single-site, double-blinded, placebo-controlled, and randomized Phase 1/2 trial of i.v. citicoline (CDP-choline) in hospitalized SARS CoV-2-infected patients with hypoxemic acute respiratory failure
Pannu S, Exline MC, Bednash JS, Englert JA, Diaz P, Bartlett A, Brock G, Wu Q, Davis IC, Crouser ED
Trials • 18 May 2024 • PMID: 38760804
Distinct patterns of SARS-CoV-2 BA.2.87.1 and JN.1 variants in immune evasion, antigenicity, and cell-cell fusion
Li P, Liu Y, Faraone JN, Hsu CC, Chamblee M, Zheng Y-M, Carlin C, Bednash JS, Horowitz JC, Mallampalli RK, Saif LJ, Oltz EM, Jones D, Li J, Gumina RJ, Liu S-L
mBio • 8 May 2024 • PMID: 38591890
Brief research report: impact of vaccination on antibody responses and mortality from severe COVID-19
Adhikari B, Bednash JS, Horowitz JC, Rubinstein MP, Vlasova AN
Frontiers in Immunology • 7 February 2024 • PMID: 38390335
Qu P, Xu K, Faraone JN, Goodarzi N, Zheng YM, Carlin C, Bednash JS, Horowitz JC, Mallampalli RK, Saif LJ, Oltz EM, Jones D, Gumina RJ, Liu SL
Cell • 1 February 2024 • PMID: 38194968
2023
Bednash JS, Johns F, Farkas D, Elhance A, Adair J, Cress K, Yount JS, Kenney AD, Londino JD, Mallampalli RK
American Journal of Respiratory Cell and Molecular Biology • May 2023 • PMID: 36730646
Bhagwani AR, Ali M, Piper B, Liu M, Hudson J, Kelly N, Bogamuwa S, Yang H, Londino JD, Bednash JS, Farkas D, Mallampalli RK, Nicolls MR, Ryan JJ, Thompson AAR, Chan SY, Gomez D, Goncharova EA, Farkas L
iScience • 5 January 2023 • PMID: 36685041
2022
Evans JP, Zeng C, Qu P, Faraone J, Zheng YM, Carlin C, Bednash JS, Zhou T, Lozanski G, Mallampalli R, Saif LJ, Oltz EM, Mohler PJ, Xu K, Gumina RJ, Liu SL
Cell Host & Microbe • 10 August 2022 • PMID: 35526534
Johnson BS, Chafin L, Farkas D, Adair J, Elhance A, Farkas L, Bednash JS, Londino JD
Molecular & Cellular Proteomics • July 2022 • PMID: 35688383
Qu P, Faraone J, Evans JP, Zou X, Zheng YM, Carlin C, Bednash JS, Lozanski G, Mallampalli RK, Saif LJ, Oltz EM, Mohler PJ, Gumina RJ, Liu SL
New England Journal of Medicine • 30 June 2022 • PMID: 35704428
Evans JP, Qu P, Zeng C, Zheng YM, Carlin C, Bednash JS, Lozanski G, Mallampalli RK, Saif LJ, Oltz EM, Mohler PJ, Gumina RJ, Liu SL
New England Journal of Medicine • 16 June 2022 • PMID: 35584183
Syrian hamsters as a model of lung injury with SARS-CoV-2 infection: Pathologic, physiologic, and detailed molecular profiling
Bednash JS, Kagan VE, Englert JA, Farkas D, Tyurina YY, Tyurin VA, Samovich SN, Farkas L, Elhance A, Johns F, Lee H, Cheng L, Majumdar A, Jones D, Rosas Mejia O, Ruane-Foster M, Londino JD, Mallampalli RK, Robinson RT
Translational Research • February 2022 • PMID: 34740873
2021
Mallampalli RK, Adair J, Elhance A, Farkas D, Chafin L, Long ME, De M, Mora AL, Rojas M, Peters V, Bednash JS, Tsai M, Londino JD
Frontiers in Immunology • 25 November 2021 • PMID: 34899695
Bednash JS, Johns F, Patel N, Smail TR, Londino JD, Mallampalli RK
Cellular Signalling • March 2021 • PMID: 33253913
2019
Douglas IS, Bednash JS, Fein DG, Mallampalli RK, Mansoori JN, Gershengorn HB
American Journal of Respiratory and Critical Care Medicine • 1 June 2019 • PMID: 30958975
Levine AR, Bain W, Bednash JS, Gladwin MT, McVerry BJ
American Journal of Respiratory Cell and Molecular Biology • February 2019 • PMID: 30476436
Chandra D, Londino J, Alexander S, Bednash JS, Zhang Y, Friedlander RM, Daskivich G, Carlisle DL, Lariviere WR, Nakassa ACI, Ross M, St Croix C, Nyunoya T, Sciurba F, Chen B, Mallampalli RK
Journal of Molecular and Cellular Cardiology • January 2019 • PMID: 30448480
2018
Bednash JS, Mallampalli RK
Methods in Molecular Biology: Proteases and Cancer • 2018 • PMID: 29318562
2017
Lendermon EA, Coon TA, Bednash JS, Weathington NM, McDyer JF, Mallampalli RK
Respiratory Research • 28 June 2017 • PMID: 28659178
Bednash JS, Weathington N, Londino J, Rojas M, Gulick DL, Fort R, Han S, McKelvey AC, Chen BB, Mallampalli RK
Nature Communications • 11 May 2017 • PMID: 28492230
2016
McKelvey AC, Lear TB, Dunn SR, Evankovich J, Londino JD, Bednash JS, Zhang Y, McVerry BJ, Liu Y, Chen BB
Elife • 2 November 2016 • PMID: 27805901
Bednash JS, Mallampalli RK
Cellular & Molecular Immunology • November 2016 • PMID: 27063466
2014
Enhancement of head and neck squamous cell carcinoma proliferation, invasion, and metastasis by tumor-associated fibroblasts in preclinical models
Wheeler SE, Shi H, Lin F, Dasari S, Bednash J, Thorne S, Watkins S, Joshi R, Thomas SM
Head & Neck: Journal for the Sciences and Specialties of the Head and Neck • March 2014 • PMID: 23728942
2012
Wheeler SE, Morariu EM, Bednash JS, Otte CG, Seethala RR, Chiosea SI, Grandis JR
Clinical Cancer Research • 15 May 2012 • PMID: 22490227
2011
Inhibition of EGFR-STAT3 signaling with erlotinib prevents carcinogenesis in a chemically-induced mouse model of oral squamous cell carcinoma
Leeman-Neill RJ, Seethala RR, Singh SV, Freilino ML, Bednash JS, Thomas SM, Panahandeh MC, Gooding WE, Joyce SC, Lingen MW, Neill DB, Grandis JR
Cancer Prevevention Research (Phila) • February 2011 • PMID: 21163936